Photodynamic Therapy is mainly used when:

there are numerous lesions over a larger area of the skin that needs to be treated.

With this method of treatment, a photosensitizing agent such aminolevulinic acid is applied to each Actinic Keratosis lesion, then applying light of a specific wavelength to the lesion, ultimately killing the cell. Strict protocols are used in this treatment, and in the US, only two are approved. The treatment has a success rate of between 69 -93%. 39

The Pros to this treatment option 33

  • Treatment of visible and non-visible lesions
  • For patients who are non compliant to topical therapies
  • Cosmetic outcome is usually excellent

Potential adverse effects include: 39

  • Initial erythema
  • Edema
  • Burning sensation
  • Pain
  • Crusting followed by hypo- hyperpigmentation
  • Ulceration
  • Scaling